Tuesdays: January 5 through May 17
4:00pm - 6:00pm
Building 50 Conference Room
(unless otherwise noted)
Final Examination - Deadline May 25, 2016
January 5 - The Age of Insight: The Quest to Understand the Unconscious in Art, Mind and Brain from Vienna 1900 to the Present
January 12 - Ebola, MERS and Likelihood of More Epidemics & Evolutionary Dynamics and Zoonotic and Cross-Species Transmission of Emerging VirusesU.S. Becomes More Vulnerable to Tropical Diseases Like Zika by Donald G. McNeil, Jr.
January 19 - The Future of Medicine: Personalized, Precision and OtherTwo unrelated middle aged women are found to have carcinoma of the lung with regional spread. Pathology of each tumor looks virtually identical. Both receive the same chemotherapeutic regimen. The first patient's tumor regresses over 90%; the second patient's tumor rapidly progresses and spreads. What accounts for this dramatic difference in response to treatment? Sections of the two cancers look alike using conventional stains. Is there a place for genomic, proteomic and metabolic analysis in explaining the clinical events? If so, can such differences be harnessed to develop specific therapeutics? Do all of the cancer cells manifest the same genomic profile? Can "all" cancers be classified by -omic analysis and thereby provide "precision" medicines? The same considerations hold true for patients with immune-mediasteed, infectious, drug reaction and other diseases? How can the huge amount of data acquired from such analyses be stored, made available and proven to be of value? These and other questions are at the forefront of consideration regarding the much-discussed "Medicine of the Future".
January 26 - Canceled Due to Weather - Rescheduled to May 17
February 2 - Where Do Viruses Come From and How Do They Do What They Do? & From A to E: 2000 Years of Hepatitis Virus History
February 9 - The Intestinal Microbiome and Inflammatory Bowel DiseaseQUIZ: Who wrote this and when?
February 16 - Atopy: The Common and The Rare Allergies in the Genomic EraAllergy - Wikipedia Description
February 23 - "Shingles" (Herpes Zoster) Revisited
March 1 - Cell Polarity: Mechanisms and Disease in the Nervous System and Liver
March 8 - Depression: Neuromodulation Meets Super-Resolution Cell BiologyDepression is a serious, widespread and increasing problem in the population at all ages and is the focus of intensive studies. Current research in depression spans structural, functional, cognitive, genomic and pharmacologic studies in humans and other species.Bridging these advances with comparable advances in super-rewsolution imaging of neural and other cells holds great promise for advancing diagnosis, understanding of mechanisms and development of therapies.
March 15 - Non Alcoholic Fatty Liver Disease and Steato-Hepatitis (NAFLD/ NASH): An "Epidemic" Liver Disease Requiring New Drugs
March 22 - Progress in Understanding Congenital Heart Disease (The #1 Killer in Birth Defects): Mechanisms and New TechnologiesCongenital heart defects are the most common type of birth defect, affect 8 out of every 1,000 newborns and more than 35,000 babies annually in the United States. Congenital heart defects involve the heart's interior walls, valves and blood vessels and range from simple defects with no symptoms to complex defects with severe, life-threatening symptoms. Remarkable advances are being made regarding understanding etiology, pathogenesis, diagnosis and treatment.
March 29 - The Oral Microbiome Meets Cell Biology and Periodontal DiseasePeriodontitis is one of the most common human inflammatory diseases affecting approximately 50% of the US adult population over the age of 30. Triggered by an altered oral microbiome, periodontal disease causes destructive inflammation that damages local tissues and can destroy the bone that supports the teeth. If untreated, periodontitis can lead to tooth loss. Periodontitis a candidate contributing factor to multiple inflammatory disease.
April 5 - Multiple Sclerosis: Mechanisms and Imaging the Process
April 12 - Global Warming: Effect on Vector Distribution, Disease and Natural Product ResearchJonathan Sleeman, MA, VetMB Director, United States Geodetic Survey, National Wildlife Health Center who will focus on environmental change and emerging diseases of wildlife and will use three examples (blue tongue virus, avian influenzas, and emerging diseases of bats) to illustrate the drivers of disease (climate change, global travel, farming practices, etc), the value of biodiversity to human health, and One Health solutions to these diseases. The USGS is responsible for tracking changes in vector and disease distribution and doing basic and epidemiological studies on mechanisms.
April 19 - Trauma in the Modern Age: Injury and Stem CellsHuge increase in civilian and military trauma
April 26 - Hepatocellular Cancer: Problems and Progress in an Epidemic DiseasePrimary cancer of the liver (HCC) used to be rare in North America but was the most common life-threatening cancer in the Orient. However, the pendulum has shifted. HCC is decreasing in the Orient (primarily due to vaccination against HBV and treatment of HCV) but is dramatically increasing in the USA. This epidemiological change has focused on the difficult problems of early diagnosis and treatment. Although improvements have taken place in both parameters, diagnosis is often "too late" and treatment, other than surgical, has made marginal inroads despite large expenditures in drug development and biomarkers.
May 3 - Cholesterol: Too Much and Too Little are Bad for Your Health
May 10 - Robotic Planetary Exploration and Thoughts about Human SpaceflightBeam up for a special lecture on human space flight and biology. Dr. Stamatios "Tom" Krimigis of the Johns Hopkins Applied Physics Laboratory will speak at the next NIH Demystifying Medicine lecture, on Tuesday, May 10, from 4:00 to 5:30 p.m. in the first-floor conference room (1227) in Bldg. 50 on the NIH campus in Bethesda. The title of his lecture is "Robotic Planetary Exploration and Thoughts about Human Spaceflight."
May 17 - How Long Can and Should We Live? & What Centenurians Teach Us about Aging
For questions about the course, please contact email@example.com.
This web page was last modified on 27 May 2016.