Cartoon: Bridging the gap between advances in biology and their application to major human diseases

Demystifying Medicine 2018

Tuesdays: January 9 through May 8
4:00pm - 6:00pm
Building 50 Conference Room
(unless otherwise noted)

Main Page
Course Materials
Speaker Profiles
Topic Introductions
Final Examination

Speaker Profiles

January 9 - New Viral Diseases, Universal Vaccines, and Removing Agents from the Blood Supply
~ Anthony S. Fauci, MD (NIAID)
~ Robert Allison, MD, MPH (CC)


January 16 - Is Childhood Leukemia Curable? Challenges and Milestones in Current Approaches
~ Nirali Shah, MD (NCI) - Biosketch
~ Haneen Shalabi, DO (NCI)


January 23 - Sexually Transmitted Diseases: Situation Getting Worse...and Also Better
~ Thomas Quinn, MD (NIAID/Johns Hopkins Bloomberg School of Public Health) -
Dr. Thomas Quinn is an NIH Distinguished Investigator and Head of the Section on International HIV and STD Research in the Laboratory of Immunoregulation at the National Institute of Allergy and Infectious Diseases. He is also Associate Director for International Research for the Division of Intramural Research at NIAID. In addition he is Professor of Medicine and Pathology in the Johns Hopkins School of Medicine and Professor of International Health, Epidemiology, and Immunology and Molecular Microbiology in The Johns Hopkins School of Public Health. In 2006, he was appointed founding Director of the Johns Hopkins Center for Global Health.

Dr. Quinn's research interests have involved laboratory and field investigations that have helped define the biological factors involved in sexual and perinatal transmission of HIV and STDs, the natural history and treatment of HIV infections, and the molecular epidemiology of HIV in Africa, the Caribbean, South America and Asia. He is a member of the National Academy of Medicine where he is Chair of the Board of Global Health. He is a member of the Association of American Physician and a Fellow of the American Association for the Advancement of Science and the Infectious Diseases Society of America. He has been an Advisor/Consultant on HIV and STDs to the World Health Organization, UNAIDS, and the U.S. Food and Drug Administration. He is an author of over 1000 publications on HIV, STDs, and infectious diseases.
~ Douglas Lowy, MD (NCI)


January 30 - Why is HIV Still a Biologic and Epidemiologic Challenge Worldwide?
~ John Coffin, PhD (Tufts/NCI) - Biosketch
~ John Mellors, MD (University of Pittsburgh) - Biosketch


February 6 - The New Frontier: Immunotherapy of Cancer
~ James Gulley, MD, PhD (NCI) - Biosketch
~ James Hodges, PhD, MBA (NCI) - Biosketch


February 13 - Does Inflammation Cause Cardiovascular Disease? If So, How?
~ Alan Remaley, MD, PhD (NHLBI)
~ Nehal Mehta, MD (NHLBI)


February 20 - The Microbiome in Man, Animals, and Disease: Where Do We Stand?
~ Yasmine Belkaid, PhD (NIAID)
~ Barbara Rehermann, MD (NIDDK) - Biosketch - Dr. Barbara Rehermann is Chief of the Immunology Section, Liver Diseases Branch in the intramural research program of NIDDK, NIH in Bethesda, Maryland, USA. Dr. Rehermann's research career started in Hannover, Germany, where she received an M.D. degree and the Venia legendi for Immunology from the Medizinische Hochschule Hannover in Germany. In addition to a clinical residency and fellowship in the Department of Gastroenterology, Hepatology and Endocrinology at the same university, she pursued a research year at the Memorial Sloan Kettering Cancer Center in New York, NY and postdoctoral research training at The Scripps Research Institute, La Jolla, CA . She directed her own laboratory as an independently funded investigator at tge Medizinische Hochschule Hannover before moving to the National Institutes of Health. Her research interests are the immunobiology and pathogenesis of viral infections, in particular those of the liver. She studies the role of innate and adaptive immune responses in viral clearance and disease pathogenesis using multidisciplinary approaches that include research with biomedical specimens from infected patients, animal models and in vitro models of virus-host cell interaction. Her work was honored with national and international awards such as the Pettenkofer Research Award, the Loeffler-Frosch Award of the German Society for Virology and the NIH Bench-to-Bedside and the NIH Director's Innovation Awards. Dr. Rehermann has served as an Associate Editor of the Journal of Immunology and is currently Consulting Editor for the Journal of Clinical Investigation and on the editorial board of the journals Gastroenterology, Hepatology, Journal of Infectious Diseases and Journal of Hepatology. She is an ad hoc reviewer for the Journal of Clinical Investigation, Journal of Experimental Medicine, Nature Medicine, Science, Immunity and others and has served as an ad hoc reviewer on NIH study sections and on national and international research committees. Dr. Rehermann is a member of the ASCI, AAP, AASLD, AAI and ASM in the US, and the DGfI and DfV in Germany. She has trained more than 45 postdoctoral fellows and students many of whom continued academic careers as physician scientists in the US, Germany, Italy, South Korea and Japan.


February 27 - The Great Neglected Diseases
~ Alan Sher, PhD (NIAID) - Dr. Phillip Gorden received a BA degree from Vanderbilt University, and an MD degree from Vanderbilt University School of Medicine. He then spent 5 years in medical residency, and endocrine metabolism fellowship at Yale University School of Medicine. In 1966, he came to the National Institutes of Health (NIH), as a clinical investigator. His early studies include the heterogeneity of polypeptide hormones, including the pro-insulin-like components of plasma, and clinical descriptions of diseases of extreme insulin resistance; particularly as related to the insulin receptor. From 1976 to 1978 he was a visiting professor in the laboratory of Lelio Orci, MD in Geneva, Switzerland, and collaborated extensively with Jean-Louis Carpentier, MD on receptor mediated endocytosis of polypeptide hormones. He further collaborated extensively with Pierre Freychet, MD on this subject. Following his return to the NIH, he served as a major branch chief, and as clinical director of the National Institute of Diabetes Digestive and Kidney Diseases (NIDDK). From 1986-1999, he served as director of NIDDK, and during his tenure a number of major clinical trials were accomplished. These include the Diabetes Control and Complication Trial (DCCT), and it's epidemiological follow-up (EDIC), as well as the diabetes prevention trial in Type 1 diabetes (DPT) and the Diabetes Prevention Program (DPP), which demonstrated a mechanism to prevent Type 2 diabetes. In 1999 he returned full time to the intramural program of NIDDK, where he is focused on developing therapeutic strategies for the extreme forms of insulin resistance, such as lipodystrophy and autoantibodies to the insulin receptor.
~ Thomas Nutman, MD (NIAID) - Biosketch


March 6 - Diabetes and Artificial Sweeteners
~ Phillip Gorden, MD (NIDDK)
~ Kristina Rother, MD (NIDDK)


March 13 - Brave New World: Imaging from the Cosmos to the Molecule
~ John Mather, PhD, (National Aeronautics and Space Administration)
~ Jennifer Lippincott-Schwartz, PhD, MS (HHMI, Janelia Research Campus)


March 20 - The Challenge of Malaria: The World's Number One Killer
~ Peter Crompton, MD, MPH (NIAID)
~ Photini Sinnis, MD, Johns Hopkins Bloomberg School of Public Health


March 27 - Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease): Are We Making Progress?
~ Bryan Traynor MD, PhD, MMSc (NIA) - Biosketch
~ Mary Kay Floeter, MD, PhD (NINDS) - Biosketch


April 3 - Compulsive Disorders: Mechanisms and Management
~ Antonello Bonci, MD (NIDA) - Biosketch
~ Veronica Alvarez, PhD (NIAAA) - Biosketch - Detailed CV


April 10 - Use of Stem Cells for Regenerative Medicine
~ Kapil Bharti, PhD (NEI) - Biosketch
~ Pamela Robey, PhD (NIDCR) - Biosketch


April 17 - The Opioid Epidemic: How, Where, and What Can Be Done?
~ Nora Volkow, MD PhD (NIDA)
~ Walter Koroshetz, MD (NINDS)


April 24 - Prenatal Genomics and Fetal Gene Therapy
~ Diana Bianchi, MD (NICHD) - Diana W. Bianchi is the Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and an associate investigator in the National Human Genome Research Institute at the National Institutes of Health (NIH). She received her M.D. from Stanford and her postgraduate training in Pediatrics, Medical Genetics and Neonatal-Perinatal Medicine at Boston Children's Hospital. She is board-certified in all three specialties. Dr. Bianchi's research focuses on noninvasive prenatal screening and development of novel fetal therapies for genetic disorders. Dr. Bianchi has published over 300 peer-reviewed articles and is one of four authors of Fetology: Diagnosis and Management of the Fetal Patient, which won the Association of American Publishers award for best textbook in clinical medicine in 2000. She is Editor-in-Chief of the International Society for Prenatal Diagnosis' (ISPD) official journal, Prenatal Diagnosis. She has held multiple leadership positions, including President of the ISPD and the Perinatal Research Society, council membership in the Society for Pediatric Research and the American Pediatric Society, and served as a board member for the American Society for Human Genetics. Dr. Bianchi has received multiple awards, including the 2015 Neonatal Landmark Award from the American Academy of Pediatrics, the 2016 Maureen Andrew Mentor Award from the Society for Pediatric Research, the 2017 Colonel Harland Sanders Award for Lifetime Achievement in Medical Genetics from the March of Dimes, and the J.E. Wallace Sterling Award for Lifetime Achievement in Medicine from Stanford University School of Medicine. In 2013 she was elected to the National Academy of Medicine.
~ Alan De Cherney, MD (NICHD)


May 1 - "Bridge Building," Careers for PhD and MD Fellow
~ Michael Gottesman, MD (OD/NCI)
~ Jonathan Yewdell, MD, PhD (NIAID)
~ Win Arias, MD (CC) - Biosketch


May 8 - The National Institutes of Hope
~ Francis Collins, MD, PhD (Director, NIH)

 

This web page was last modified on 19 April 2018.
For questions about the course, please contact ariasi@mail.nih.gov.